1: Chung Kuo Chung Hsi I Chieh Ho Tsa Chih 1994 Apr;14(4):227-229
[Pharmacological action of 101-B
hair regeneration extract on skin and hair in experimental
animals]
[Article in Chinese]
Qian BC, Chen
J, Xu HJ.
Inst. of Materia Medica, Zhejiang Academy of
Medical Sciences, Hangzhou.
Pharmacological action of 101-B hair
regeneration extract (101-B) on skin and hair was studied in
experimental animals. The results were as follows: (1) In normal rats,
guinea pigs and rabbits the weight of regrown hairs in shaved area in
101-B group was significantly heavier than that in alcohol group. (2)
Hair loss induced by oral administration of thallium carbonate 2 mg/kg
every other day for 10 times was obviously prevented by topical
treatment of 101-B. (3) Itching threshold to histamine or papain in
guinea pig was elevated after using of 101-B topically. (4) The diameter
of skin ulcer caused by intradermal injection of adriamycin in rats was
diminished in 101-B group. (5) Observation in skin microcirculation in
mice indicated that both normal skin microcirculation and disturbed
microcirculation induced by endotoxin were improved with administration
of 101-B. Above experimental results provided preliminary evidence for
clinical use of 101-B.